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The following Special Issue on the “Prevention, Diagnosis and Treatments of Early-Stage NSCLC: New Advances and Future Prospective” forms a collection of articles showcasing the latest scientific progress in this field, focusing particular attention on minimally invasive techniques such as video-assisted thoracic surgery (VATS) and robotic-assisted thoracic surgery (RATS) compared to open surgery both for early and long-term outcomes in addition to the role of sublobar resection for the treatment of early-stage NSCLC compared to lobectomy. Moreover, we also focus on the importance of recently identified potential biomarkers such as TLR expression to be used for future prognostic purposes in NSCLC and the importance of enhancing immune response in NSCLC patients with the use of the 13-valent pneumococcal conjugate vaccine (PCV13).

The book starts with the editors’ preface summarizing the contributions of each of the following thirteen articles dealing with chemical and pharmacological aspects of the molecular modulators of the oxidative stress in regard to various therapeutic approaches in cardiovascular and neurodegenerative diseases, cancer, and diabetes. The seven articles present data from original research studies enlightening the roles and mechanisms of action of small molecular weight compounds (natural and synthetic; ascorbic acid/vitamin C, deferoxamine, N-acetylcysteine, MitoVitE, α-tocopherol, trolox, and ezetimibe) or proteins (SIRT3) in modulation of oxidative stress. In the six review papers, the authors present and discuss the possible therapeutic potential of novel approaches and compounds that are promising and deserve further investigation, in modulation of oxidative stress. Related Books Oxidative Stress Modulators and Functional Foods Medicine & Pharmacology Cellular and Molecular Mechanisms

Colloids, such as emulsions, foams, sols, and gels, play an integral role in living organisms, the natural environment, resource extraction, pharmaceuticals, cleaning products, processing industries, and basically, in almost all aspects of our everyday life. To a large extent, colloid stability and functionality are determined by the properties of interfaces between dispersed and continuous phases and by the surface forces acting at micro- and nanoscale levels. It is the amphiphilic molecules that are capable of altering colloidal system properties, thus changing the overall system behavior. This is why a comprehensive understanding of the amphiphile molecular structure and the respective interactions taking place at the interfaces ensures effective control over colloidal system properties. The contributions included in this Reprint highlight the relation between amphiphile molecular structure, self-assembly in solutions, molecular arrangements at interfaces, specific interactions at micro- and nanoscales, and the properties displayed by the colloidal systems. The included research spans from fundamental studies on the physicochemical behavior of colloidal systems to the design of innovative solutions for practical applications.

This Reprint will consider developments in advanced  cold spray technology, exploring its innovative applications and transformative impacts across various industries. Cold spray technology, with its ability to deposit coatings and fabricate parts without melting the feedstock, offers unique advantages such as minimal thermal distortion, high deposition rates, and the ability to work with a wide range of materials. In this Reprint , we present a collection of cutting-edge studies and expert insights that showcase the latest advancements in cold spray techniques, equipment, and applications. This compilation includes studies on the optimization of process parameters, development of new materials, and enhancement of coating properties to meet the demanding requirements of the aerospace, automotive, and biomedical sectors, among others. By highlighting breakthroughs in surface engineering, the repair and restoration of components, and additive manufacturing, we will  improve our  understanding of the current state and future potential of cold spray technology.

Discover the complexities of pediatric orthopedics in this comprehensive reprint book. Pediatric orthopedics present unique challenges in diagnosis and treatment, necessitating the expertise of skilled specialists. Congenital, developmental, and acquired orthopedic issues, including infectious, neuromuscular, nutritional, neoplastic, psychogenic, and traumatic conditions, are explored. With a focus on evidence-based recommendations, this book addresses the management of orthopedic deformities in children by considering different clinical scenarios. From upper and lower limb injuries to severe trauma, readers will gain insights into decision-making processes for reconstruction or amputation. As a valuable resource for orthopedic surgeons, pediatricians, and healthcare professionals, this reprint fills knowledge gaps to optimize patient care. Related Books Pediatric Fractures Medicine & Pharmacology Pediatric Fractures—Volume II Medicine & Pharmacology Acute Trauma and Trauma Care in

This Reprint, entitled “Cadmium and Trace Elements Toxicity,” brings together ten high-quality research articles that advance our understanding of the sources, mechanisms, and health impacts of cadmium and trace element exposure. The contributions span multiple disciplines, from molecular toxicology and environmental monitoring to plant science and risk assessment, providing a comprehensive overview of current research in this critical field. The articles address key topics including novel toxicity mechanisms, biomonitoring approaches, protective strategies, and environmental quality criteria.

Slaughter animals are transported, lairaged and stunned before slaughter. The welfare of animals can be compromised during this period. It is expected that all animals be protected from avoidable sources of disturbance, pain, or suffering during transport, lairage, restraint, stunning, slaughter, or killing. Slaughter animals include horses, ruminants, pigs, poultry, and species of fish. The different aspects involved in handling these animals are described in each chapter.

This Special Issue of the International Journal of Molecular Sciences (IJMS), entitled “Molecular Mechanism in Epithelial-Mesenchymal Transition (EMT) and Fibrosis”, collected 15 original research papers (5 reviews and 10 articles) written by a panel of experts from different countries who highlight recent advances in the EMT process.Navigating the complex field of EMT, this Special Issue introduces the current understanding of the underlying mechanisms of EMT in the evolution and progression of fibrogenesis and discusses potential strategies for attenuating EMT to prevent and/or inhibit fibrosis.Overall, the 15 scientific articles in this Special Issue of the International Journal of Molecular Sciences provide valuable insights into the complex mechanisms governing the EMT process linked to fibrosis and have highlighted the potential of novel therapeutic strategies. In the last few years, the field of EMT has shown considerable promise, and there is still much to be learned. As our

Graphene is a two-dimensional, one-atom-thick material made entirely of carbon atoms, arranged in a honeycomb lattice. Because of its distinctive mechanical (e.g., high strength and flexibility) and electronic (great electrical and thermal conductivities) properties, graphene is an ideal candidate in myriad applications. Thus, it has just begun to be engineered in electronics, photonics, biomedicine, and polymer-based composites, to name a few. The broad family of graphene nanomaterials (including graphene nanoplatelets, graphene oxide, graphene quantum dots, and many more) go beyond and aim higher than mere single-layer (‘pristine’) graphene, and thus, their potential has sparked the current Special Issue. In it, 18 contributions (comprising 14 research articles and 4 reviews) have portrayed probably the most interesting lines as regards future and tangible uses of graphene derivatives. Ultimately, understanding the properties of the graphene family of nanomaterials is crucial for d

This Special Issue Reprint compiles cutting-edge research on Unmanned Aerial Vehicles (UAVs), highlighting transformative advancements that broaden their capabilities across diverse sectors. Bringing together contributions from researchers, practitioners, and industry experts, this collection fosters interdisciplinary dialogue while delivering rigorous peer-reviewed insights into UAV technology and services. It covers a comprehensive range of critical topics, such as the following: autonomous navigation and control systems (including advanced algorithms for obstacle detection, path planning, and formation flying); innovative sensing/imaging technologies (hyperspectral imaging, LiDAR, thermal imaging for data acquisition); efficient communication/networking solutions (reliable, secure connectivity, network coordination, swarm intelligence for networked UAVs); payload design and service delivery (medical supply transport, infrastructure inspections); energy efficiency research (energy harvesting, optimization algorithms, sustainable power sources); and regulatory/ethical considerations for safe, responsible UAV deployment. Featuring original research articles, reviews, and case studies, this Reprint captures the latest breakthroughs pushing UAV application boundaries. It serves as an invaluable resource for professionals and researchers seeking to keep up to date with industry progress, inspiring further innovation and collaboration to advance UAV technology’s real-world impact.

Standards can be international, national, regional, or corporate. They cover production and consumption, social responsibility, health and safety, quality management, laboratories, diverse devices, and equipment, to mention the most popular ones. They are the basis for our everyday activities: air, water, and food quality, information security, codes, accounting, reporting, etc. Despite the great number of existing standards, new and improved ones are appearing daily. The standardization process includes development, acceptance, and implementation of new or improved standards. The stakeholders can be companies, standardization institutions, governments, users, interest groups, professionals, and scientists. The international organization for standardization, ISO, has a guidance document on new work with three parts: 1) new standardized areas, 2) new fields of work, and 3) new work item proposals within existing committees. New standards need to be inspected, verified, and their quali

Nowadays, we use the term “modern endodontics” thanks to new technologies, novel materials, and revolutionary techniques. Various equipment is available to facilitate and improve our endodontic treatments, such as operating microscopes, ultrasounds, lasers, modern alloys for rotary files, powerful irrigation systems, new materials for filling root canals, 3D radiology, and several more. With the aid of the previously mentioned advances, complex endodontic treatments can be carried out safely, hence guaranteeing patients a high level of care and, above all, saving teeth that would otherwise be doomed for extraction. General practitioners and, even more importantly, specialists in endodontics should implement these modern technologies in their practice. This Special Issue will focus on modern endodontics regarding all the recent updates. Full papers of original articles, short communications, and review articles are all invited. Related Books Advanced Materials and Technologies in End

Molecular modeling has revolutionized the ways in which we understand, predict, and manipulate chemical systems, from simple molecules to complex biological macromaterials and functional nanomaterials. By bridging theory and experiment, computational approaches provide unprecedented insights into atomic-scale interactions, reaction mechanisms, and material properties, accelerating discovery across chemistry, biochemistry, and materials science. This Reprint of the Special Issue entitled “Advances in Molecular Modeling in Chemistry” aims to showcase cutting-edge developments in computational chemistry and molecular simulation. The Special Issue highlights innovative methodologies, algorithms, and applications in areas such as quantum chemical calculations, molecular dynamics and Monte Carlo simulations, machine learning and artificial intelligence in chemical modeling, etc. The studies published within this Reprint explore areas such as molecular dynamics simulations of oil adsorption behavior, the antifoaming mechanisms of surfactants, density functional theory calculations of catalytic mechanisms, drug discovery, and the evaluation of combustion mechanisms using reactive molecule force fields, among other topics. By bringing together diverse expertise, this Special Issue seeks to foster interdisciplinary dialog and inspire the next generation of computational strategies.

The aim of this reprint is to emphasize the crucial role of mineral chemistry in understanding the crystallization parameters (temperature, pressure, and oxygen fugacity) during the petrological evolution of granitic magmas. Contributions from leading experts in the field offer fresh perspectives and in-depth analyses, enhancing our understanding of granitic systems and their broader geological significance. Given that the chemistry and redox conditions of the parental magma significantly influence the composition of minerals in granites, this reprint highlights the importance of mineral chemistry in unraveling magmatic processes, ranging from conventional mineral chemistry, involving the analysis of primary ferromagnesian phases that provide valuable insights into the nature of the magma and its affinity with various magmatic series, to more recent approaches that involve studying trace element signatures in accessory minerals to trace the source and petrological evolution of granitic magmas. This reprint demonstrates how these methods serve as powerful tools for studying granitic systems by employing less mobile chemical signatures to complement conventional mineral chemistry data.

This reprint contains the scientific contributions from a Special Issue dedicated to multi-agent system analysis and optimization from a broad perspective (including branches potentially applicable in multi-agent systems). Related Books Multi-Agent Systems Engineering Multi-Agent Systems 2019 Engineering Mathematical Methods Applied in Artificial Intelligence and Multi-Agent Systems Computer Science & Mathematics Multi-Robot Systems: Challenges, Trends and Applications Engineering Machine-Learning-Assisted Intelligent Processing and Optimization of Complex Systems Computer Science & Mathematics The recommendations have been generated using an AI system. About: About MDPI Books Advisory Board Legal Information: MDPI Privacy Policy Terms and Conditions Terms of Use Accessibility Sales: Order and Delivery Indexing and Distribution Further Information: Book Series Reprints Book/Chapter Processing Charges Pay an Invoice Open Access Policy Obtaining an ISBN For Librarians MDPI I

This Special Issue, entitled the “Synthesis of Heteroaromatic Compounds”, is an outstanding collection of fourteen original research papers and six review articles that discuss the advances made in both conventional and green preparatory methods, as well as the properties and applications of heteroaromatic molecules in industrial and medicinal chemistry areas of study.The collected works featured herein collate contributions from a truly international and diverse array of ninety experts in the fields of heteroaromatic compound synthesis, QSAR studies, computational chemistry and molecular docking, as well as bioactivity studies. Related Books Advances in the Synthesis of Heterocyclic Compounds and Their Applications Chemistry & Materials Science Modern Strategies for Heterocycle Synthesis Medicine & Pharmacology ... Heterocyclic Compounds in Medicinal Chemistry Biology & Life Sciences Recent Developments in the Synthesis and Functionalization of Nitrogen Heterocycles Chemistry & Mat

The development of modern measurement methods for ship systems results from economic changes and increasingly stringent environmental requirements. Additionally, the specificity of ship systems and the conditions in which they work lead to very restrictive requirements for the reliability and accuracy of measuring systems on ships and offshore facilities. This collection presents the results of research related to the development of modern systems on ships and offshore facilities, with a particular focus on the measurement and assessment of processes occurring in ship propulsion systems, ship navigation systems, maritime communications, maritime safety and alarm systems, marine cargo-handling equipment, offshore technological systems, etc. This book addresses all types of sensors and measurement systems designed for ships and offshore facilities. Related Books Sensors and Measurement Systems for Marine Engineering Applications Engineering Selected Papers from the 2018 IEEE Internati

Bakery products such as bread, rolls, cookies, pies, pastries, bars, and muffins play a significant role in the daily diet of modern consumers. The growing interest in the health benefits of food has driven the development of new products and the adaptation of traditional recipes and technologies. These changes also extend to bakery products, which, depending on their composition, can be excellent sources of complex carbohydrates (e.g., starch and dietary fiber), proteins, vitamins, minerals, and phytochemicals that positively impact the human body. This reprint immerses readers in the latest research on the potential of modifying bakery products. It explores how technologies and biotechnologies can be employed to enhance, remove, alter, or improve the bioavailability of components, transforming baked goods into functional foods. The functional and health properties of bakery products depend not only on the nutrient content, but also on the various methods of food processing. For anyone interested in modern food innovation and healthy eating, this reprint serves as an inspiring resource for shaping the future of bakery products.

This Special Issue on "Carbon Dioxide Capture, Utilization and Storage (CCUS)" features invited articles on the latest technologies and developments in CCUS, including but not limited to pre-combustion carbon capture; post-combustion carbon capture; oxyfuel or chemical cycle combustion; conversion of CO2 to synthetic fuels; biomass thermal conversion; CO2 storage; BECCUS; and other abatement technologies. Related Books Advances in Carbon Capture, Utilization and Storage (CCUS) Environmental & Earth Sciences Advances in Carbon Capture, Utilization and Storage Technologies (CCUS) Environmental & Earth Sciences ... CO2 Capture and Sequestration Social Sciences, Arts & Humanities ... Catalytic Processes for CO Utilization Chemistry & Materials Science ... Application and Optimization of CCUS Technology in Shale Gas Production and Storage Engineering The recommendations have been generated using an AI system. About: About MDPI Books Advisory Board Legal Information: MDPI Privacy Pol

The aim of the Special Issue “Applications of Fuzzy Optimization and Fuzzy Decision Making” is to expand the applicability of fuzzy optimization and decision making for solving various types of problems in the areas of economics, business, engineering, management, operations research, etc. Any experimental research or empirical study of theoretical developments in fuzzy optimization and decision making is highly welcome. Additionally, research papers presenting solution methods and/or studying their computational complexity, and proposing new algorithms to solve fuzzy optimization and decision making problems, in an effective and efficient manner, are also welcome. We are looking forward to receive innovative approaches that apply, in practical settings, state-of-the art mathematical/algorithmic techniques from fuzzy technology, computational intelligence and soft-computing methodologies, with the aim to offer robust solutions for complex optimization and decision making problems cha

The present book focuses on that part of calculus of variations, optimization, nonlinear analysis and related applications which combines tools and methods from partial differential equations with geometrical techniques. More precisely, this work is devoted to nonlinear problems coming from different areas, with particular reference to those introducing new techniques capable of solving a wide range of problems. The book is a valuable guide for researchers, engineers and students in the field of mathematics, operations research, optimal control science, artificial intelligence, management science and economics. Related Books Nonlinear Analysis and Optimization with Applications Computer Science & Mathematics New Theory and Applications of Nonlinear Analysis, Fractional Calculus and Optimization Computer Science & Mathematics Nonlinear Functional Analysis and Its Applications Computer Science & Mathematics Mathematical and Numerical Analysis of Nonlinear Evolution Equations Biology &

Cultural heritage, especially the fine arts, plays an invaluable role in the cultural, historical, and economic growth of our societies. Works of fine art are primarily developed for aesthetic purposes and mainly expressed through painting, sculpture, and architecture. In recent years, owing to technological improvements and drastic cost reductions, a large-scale digitization effort has been made, which has led to the increasing availability of large, digitized fine art collections. Coupled with recent advances in pattern recognition and computer vision, this availability has provided, especially for researchers in these fields, new opportunities to assist the art community by using automatic tools to further analyze and understand works of fine arts. Among other benefits, a deeper understanding of the fine arts has the potential to make these works more accessible to a wider population, in terms of both fruition and creation, thus supporting the spread of culture. Related Books Adv

This book covers several research items related to LLC resonant converters, which were published in a Special Issue of Energies on the subject area of "Advances in High-Efficiency LLC Resonant converter". It focuses on emerging power electronic topologies related to the LLC resonant converter, and its design methodology and control algorithms. Topics of interest include LLC resonant topologies, resonant tank design methodology for high efficiency, power loss analysis in LLC resonant converters, high-frequency magnetics for resonant converters, wide band-gap devices applied to LLC resonant converter, and advanced control algorithm for LLC resonant converter. Related Books Design and Control of Power Converters 2020 Engineering Design and Control of Power Converters 2019 Engineering Advanced DC-DC Power Converters and Switching Converters II Engineering High-Efficiency and High-Performance Power Electronics for Power Grids and Electrical Drives Engineering Multilevel Converters: Analysi

Modern industry, driven by the recent environmental policies, faces an urgent need for the production of lighter and more environmentally-friendly components. High-strength low-alloy steels are key materials in this challenging scenario because they provide a balanced combination of properties, such as strength, toughness, formability, weldability, and corrosion resistance. These features make them ideal for a myriad of engineering applications which experience complex loading conditions and aggressive media, such as aeronautical and automotive components, railway parts, offshore structures, oil and gas pipelines, power transmission towers, and construction machinery, among others. The goal of this book is to foster the dissemination of the latest research devoted to high-strength low-alloy (HSLA) steels from different perspectives. Related Books Recent Trends in Advanced High-Strength Steels Engineering Mechanical Behavior of High-Strength Low-Alloy Steels Engineering Light Alloys